a real Zeal difference


Clinical trial proves two Zeals per day make a real Zeal difference.


Zurvita Clinical Trial – Highlights



The objective of this study was to investigate the effect of Zeal on healthy, moderately stressed adults using standardized measures of mood states, including overall feelings of vitality.


The study design called for 100 healthy, moderately stressed adults  with 25 participants randomized equally to each of the 4 study arms in a double-blind manner.


Definition of the Study Populations:

The Per Protocol Population consisted of 84 of the 99 participants who actually started the trial and who did not have any major protocol

violations, and completed all study visits and procedures connected with measurement of the primary variable.


These eighty-four participants were analyzed in the “Per Protocol” Population, with 21 participants in the Zeal once daily group, 20 participants in the Zeal twice daily group, 23 participants in the Placebo once daily group, and 20 participants in the placebo twice daily group.


Ninety-nine participants with an age range of 18 – 65 years and a BMI of 18.4 – 30.1 kg/m2 were enrolled in this study. Participants were predominantly Caucasian and non-smokers with 62% females and 38% males. All participants were deemed healthy by physical examination and as per their screening laboratory parameters.


The stress levels of participants, based on the Stress/Vitality questionnaire confirmed that they were moderately stressed. 71% percent of the participants confirmed self-reported moderate stress. 81% self-reported ups and downs in energy level and 65% were tired by mid-afternoon during the day. Forty percent did not engage in any exercise while 38% were engaged in moderate levels of exercise.

88% were non-smokers and 52% were light alcohol drinkers (≤ 1 drink/week). 30% of the participants were married and 68% did not have children. 53% worked full time while 23% were either seeking employment or were unemployed. 36% percent consumed a typical American diet, 87% did not take supplements and 79% consumed caffeine in the form of coffee (54%).


Compliance with the study protocol in all groups were >90%.


All subjects were recruited from the Orlando, Florida metropolitan area and the study was completed prior to any of the recent occurrences in the Orlando area.

Based on the results of the two placebo groups, they were combined in order to gain additional statistical power.


The results of this analysis were provided both by the results of the intent-to treat and the per-protocol analysis. However, this summary focuses on the 2-day Zeal results to be consistent with the use recommendations of Zurvita. An extension of the POMS, the POMS Iceberg profile, designed for assessing active/healthy individuals was also analyzed.


Zeal at a dose of 28 grams per day, consumed as two doses of 14 grams, one in the morning and one mid-afternoon, signficantly improved mood states and reduced stress levels within 29 days in moderately stressed but otherwise healthy individuals. This “Gold Standard” randomized double-blind, placebo-controlled clinical study scientifically validated zeal drink in a healthy population by testing the efficacy of the product using proven research tools that test mood states.


Though this study had a 16% placebo effect, statistically significant improvements in Profile of Mood State-Total Mood Disturbance were achieved compared to a combined Placebo group. Participants reported a significant decrease of approximately 7% in the POMS-TMD and its subdomain, Anger and Hostility compared to the combined Placebo

when they consumed 28 g of Zeal daily in two separate doses, one in the morning and one mid-afternoon.


2-dose Zeal improved the POMS Iceberg profile with a significant within group increase in Vigor and Activity. This improvement was associated with a significant within group decrease in the POMS subdomains of Tension and Anxiety, Despondency and Dejection, Anger

and Hostility, Fatigue and Inertia, Confusion and Bewilderment.


Rejuvenation of mood states, particularly reductions in anxiety and despondency in this study corroborates earlier investigations into the anxiolytic and mood supporting properties of multiple food derived ingredients in the Zeal formulation, including Maca (Lepidium meyenii) (Stojanovska L et al., 2015) and grape seed extract (Terauchi M et al., 2014).


Importantly, the safety and efficacy profile of Zeal in this study strengthens evidence for its use in a healthy population to address moderate stress.


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